-5%
Empazin M 12.5|500 is used as a treatment for adults with type 2 diabetes mellitus.
- Swallow tablets whole with food.
- Do not crush, chew, or break the tablet.
- Take the medication at the same time each day.
- If a dose is missed, take it as soon as remembered.
- Skip the missed dose if it is nearly time for the next one.
- Do not double-dose.
- Not recommended during pregnancy, especially during the 2nd and 3rd trimesters.
- Not advised during breastfeeding as both components may be excreted in breast milk and pose a risk to the infant.
Empazin M 12.5/500 is indicated for the management of Type 2 Diabetes Mellitus in adults, as an adjunct to diet and exercise, especially in patients where a combination therapy is appropriate.
This fixed-dose combination works via dual mechanisms:
- Empagliflozin: Inhibits the SGLT2 transporter in the kidneys, promoting urinary excretion of glucose by preventing its reabsorption.
- Metformin: Reduces hepatic glucose production and enhances insulin sensitivity, improving glucose uptake by peripheral tissues.
Together, they synergistically lower blood glucose levels in patients with type 2 diabetes.