-2%
Pregabalin, a structural derivative of gamma-aminobutyric acid (GABA), does not directly interact with GABA receptors or benzodiazepine receptors. Instead, it binds with high affinity to the alpha2-delta subunit of voltage-gated calcium channels in the central nervous system. Although its precise mechanism of action is not fully understood, studies suggest that this binding contributes to Pregabalin’s anti-seizure and anti-nociceptive effects.
