-5%
Precodil 5 mg is a synthetic corticosteroid with glucocorticoid properties. It inhibits the enzyme phospholipase A2, preventing the production of inflammatory mediators like leukotrienes, SRS-A, and prostaglandins. It is rapidly absorbed from the gastrointestinal tract, with 70-90% plasma protein binding and a half-life of 2–4 hours. It is metabolized in the liver and excreted in urine.
Rheumatic Disorders: Used for managing conditions such as psoriatic arthritis, rheumatoid arthritis, juvenile rheumatoid arthritis, ankylosing spondylitis, acute and subacute bursitis, acute nonspecific tenosynovitis, acute gouty arthritis, and post-traumatic osteoarthritis.
Endocrine Disorders: Effective for primary or secondary adrenocortical insufficiency, congenital adrenal hyperplasia, nonsuppurative thyroiditis, and hypercalcemia associated with cancer.
Dermatologic Conditions: Treats severe skin disorders like pemphigus, bullous dermatitis herpetiformis, severe erythema multiforme, exfoliative dermatitis, mycosis fungoides, and severe psoriasis.
Allergic Conditions: Relieve seasonal or perennial allergic rhinitis, bronchial asthma, contact dermatitis, atopic dermatitis, serum sickness, and drug hypersensitivity reactions.
Respiratory Disorders: Used for conditions such as symptomatic sarcoidosis, berylliosis, fulminating aspiration pneumonitis, and severe lung infections.
Hematologic Disorders: Manages idiopathic thrombocytopenic purpura, secondary thrombocytopenia, acquired autoimmune hemolytic anemia, erythroblastopenia, and RBC anemia.
Edematous States: Induces diuresis and remission of proteinuria in nephrotic syndrome without uremia, including cases caused by lupus erythematosus.
Gastrointestinal Diseases: Effective for managing ulcerative colitis and regional enteritis.