Levocar 330mg-6pcs Tablet

The supplemental Levocarnitine use is widely established in the management of cardiac ischemia and peripheral arterial disease. It is generally indicated for cardio protection. It lowers triglyceride levels and increases levels of HDL cholesterol. It is used with benefits in those with primary and secondary carnitine deficiency syndromes. There is also evidence of its use in liver, kidney and immune disorders or in diabetes and Alzheimer’s disease. There is little evidence that supplemental Levocarnitine boosts energy, increases athletic performance or inhibits obesity. The indications of Levocarnitine may be summarized as follows:
 

• Heart Diseases
• Congestive Heart Failure
• Kidney Disease
• Chronic Fatigue Syndrome
• High Cholesterol
• Intermittent Claudication
• Dementia and memory impairment
• Down Syndrome
• Male infertility
• Hyperthyroidism

Alcohol	CONSULT YOUR DOCTOR It is not known whether it is safe to consume alcohol with Levocar. Please consult your doctor.
Pregnancy	SAFE IF PRESCRIBED Levocar is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breastfeeding	SAFE IF PRESCRIBED Levocar is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving	SAFE Levocar does not usually affect your ability to drive.
Kidney	CAUTION Levocar should be used with caution in patients with kidney disease. Dose adjustment of Levocar may be needed. Please consult your doctor.
Liver	SAFE IF PRESCRIBED Levocar is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Levocar may not be needed in these patients. Please consult your doctor.

Medical Overview

Introduction

Levocar belongs to a class of medications called amino acids. It is used in the treatment of carnitine deficiency. It helps the body produce energy and improve the efficiency of body function. Levocar should be taken with food and it should be chewed thoroughly before swallowing. Take it in the dose and duration as advised by your doctor. Do not start or stop taking this medicine without a doctor’s prescription. Levocar is usually a safe medicine, however, it may cause nausea and vomiting. Your doctor may suggest you to monitor your blood glucose levels regularly while you are taking the medicine. Before starting the medicine, inform your doctor if you have any other medical conditions or are taking any other medications. Patients with severe kidney disease should not take this medicine unless prescribed by the doctor.

Uses of Levocar

• Carnitine deficiency

Side effects of Levocar

Common

• Vomiting
• Nausea

How to use Levocar

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Levocar is to be taken with food.

How Levocar works

Levocarnitine belongs to the class of medications called as amino acid derivative. It works by improving the low levels of carnitine in the body.

Quick Tips

• It is given as a slow injection into veins under the supervision of a doctor.
• Monitor your blood glucose levels regularly during levocarnitine treatment.
• Tell your doctor if you are pregnant, planning to become pregnant or are breastfeeding.

Brief Description

Indication

Congestive heart failure, Diabetic nephropathy, Intermittent claudication, Kidney disease, Chronic Fatigue Syndrome, Heart Diseases, High Cholesterol, Dementia and Memory impairment, Down Syndrome, Male infertility

Administration

Consume oral solution slowly, may be mixed with drinks and space doses evenly throughout the day (q3-4hr) preferably during or after meals (may decrease GI distress)

Adult Dose

Adults: Tablet: 330 mg two or three times daily.

Child Dose

Infants and children: 50 to 100 mg/kg/day in divided doses, with a maximum of 3 g/day. Dosage should begin at 50 mg/kg/day. The exact dosage will depend on clinical response.

Contraindication

Hypersensitivity.

Mode of Action

Quaternary ammonium compound found in all mammalian tissue (particularly striated muscle). Important for lipid catabolism; essential for FFA transport from cytosol to mitochondria where they are oxidized.

Precaution

Gastrointestinal reactions may result from a too rapid consumption of Levocarnitine. The safety and efficacy of oral levocarnitine has not been evaluated in patients with renal insufficiency. Chronic administration of high doses of oral levocarnitine in patients with severely compromised renal function or in ESRD patients on dialysis may result in accumulation of the potentially toxic metabolites, trimethylamine (TMA) and trimethylamine-N-oxide (TMAO), since these metabolites are normally excreted in the urine

Side Effect

Generally Levocarnitine is well tolerated. However, few side effects including transient nausea and vomiting, abdominal cramps, and diarrhoea may occur