-4%
Lidocaine produces its local anesthetic effect by blocking sodium ion movement through voltage-gated sodium channels in nerve cell membranes. This action prevents the initiation and transmission of nerve impulses, resulting in loss of sensation. Lidocaine binds more effectively to activated sodium channels, allowing faster onset of nerve blockade in rapidly firing neurons—an effect known as state-dependent blockade.
Jasocaine is a topical local anesthetic used to reduce pain and discomfort in various clinical settings, including:
Relief of pain during minor surgical procedures involving the ear, nose, and throat
Minimizing discomfort during dental procedures, such as prior to local anesthetic injections
Suppression of coughing during general anesthesia
Pain relief during the late stages of childbirth, including procedures involving incision or suturing of the perineum