-5%
Benzit consists of Flupentixol & Melitracen. This is used to treat Anxiety, Depression, apathy, Psychogenic depression, Depressive neurosses, Masked depression, and menopausal depression.
Overdose Management
Symptoms are typically dominated by melitracen toxicity, presenting as anticholinergic effects; extrapyramidal reactions due to flupentixol may occur rarely.
Treatment:
- Immediate gastric lavage and activated charcoal administration.
- Supportive measures for respiratory and cardiovascular function.
- Avoid epinephrine (adrenaline).
- Diazepam may be used for convulsions and biperiden for extrapyramidal symptoms.
Adverse effects are uncommon at recommended doses but may include temporary restlessness or insomnia
Benzit combines two clinically proven active ingredients:
Flupentixol – a neuroleptic agent with anxiolytic and mild antidepressant effects when taken in low doses.
Melitracen – a tricyclic antidepressant (thymoleptic) that exhibits activating and mood-elevating properties at low doses.
Together, these compounds provide a synergistic antidepressant, anxiolytic, and activating effect.
After oral administration, both drugs reach peak plasma concentrations within approximately 4 hours. The elimination half-life of flupentixol is about 35 hours, while melitracen’s is around 19 hours. The combination does not alter the pharmacokinetic behavior of either compound.