-5%
This cream combines the potent topical antibacterial activity of fusidic acid with the anti-inflammatory and anti-pruritic activity of the moderately potent corticosteroid betamethasone valerate. When applied topically, fusidic acid is effective against Staphylococci, Streptococci, Corynebacteria, Neisseria and certain Clostridia and Bacteroides. The antibacterial activity of fusidic acid is not diminished in the presence of betamethasone.
- Fusidic Acid: Works against gram-positive bacteria (e.g., Staphylococcus aureus, Streptococcus, Corynebacterium minutissimum) by inhibiting bacterial protein synthesis. It blocks amino acid transfer from aminoacyl-tRNA to protein formation on ribosomes.
- Betamethasone: A corticosteroid that induces lipocortin, inhibiting the phospholipase A-2 enzyme, which reduces inflammatory mediators such as prostaglandins, kinins, and histamines.