Esonix 40mg Capsule 10pcs

Indications

40mg of Esonix A medication known as a capsule lowers the amount of acid your stomach produces. Heartburn, acid reflux, and issues with your food pipe are all treated with it. Stomach ulcers can also be prevented and treated with them.

Pharmacology

By specifically inhibiting the H+/K+-ATPase in the gastric parietal cell, the proton pump inhibitor esomeprazole reduces stomach acid output. Esomeprazole (omeprazole’s S-isomer) is the first proton pump inhibitor with a single optical isomer and offers superior acid control over racemic proton pump inhibitors.

Dosage

• Healing of Erosive Esophagitis: 20 mg or 40 mg Once Daily for 4-8 Weeks. The majority of patients are healed within 4 to 8 weeks. For patients who don’t heal after 4-8 weeks, an additional 4-8 weeks of treatment may be considered. Maintenance of Healing of Erosive
• Esophagitis: 20 mg Once Daily (Clinical studies did not extend 6 months).
• Symptomatic GERD: 20 mg Once Daily for 4 Weeks. If symptoms do not resolve completely after 4 weeks, an additional 4 weeks of treatment may be considered.
• Helicobacter Pylori eradication: Triple Therapy to reduce the risk of Duodenal Ulcer recurrence-Esomeprazole 40 mg Once Daily for 10 days, Amoxicillin 1000 mg Twice Daily for 10 days, Clarithromycin 500 mg Twice Daily for 10 days.
• Zollinger-Ellison Syndrome: The dose is 20-80 mg once daily. The dosage should be adjusted individually and treatment continued as long as clinically indicated.
• Acid-related Dyspepsia: 20-40 mg once daily for 2-4 weeks according to the response.
• Duodenal ulcer: 20 mg once daily for 2-4 weeks. Gastric ulcer: 20-40 mg once daily for 4-8 weeks.

Administration

Esomeprazole tablet or Capsule: should be swallowed whole and taken one hour before a meal.

Interaction

CYP2C19 and CYP3A4 substantially metabolize esomeprazole in the liver. Esomeprazole is not expected to inhibit CYPs 1A2, 2A6, 2C9, 2D6, 2E1, and 3A4, according to in vitro and in vivo research. There shouldn’t be any clinically significant interactions with medications that these CYP enzymes process. According to studies on drug interactions, esomeprazole does not interact clinically with phenytoin, warfarin, quinidine, clarithromycin, or amoxicillin.

Contraindications

Esonix 40 has contraindicated in-patient with known hypersensitivity to any of the formulations.

Side Effects

• Headache
• Dizziness
• Dryness in mouth
• Nausea
• Abdominal pain
• Constipation
• Flatulence
• Diarrhea

Pregnancy & Lactation

There are no adequate and well-controlled studies on pregnant women. Animal studies have revealed no teratogenic effects. The excretion of esomeprazole in milk has not been studied. Breastfeeding should therefore be discontinued if the use of esomeprazole is considered essential.

Precautions & Warnings

• General: Symptomatic response to therapy with esomeprazole does not preclude the presence of gastric malignancy.
• Patients should take Esonix 40 capsules at least an hour before meals, according to information. 
• One spoonful of applesauce can be put into an empty bowl, the Esomeprazole capsules can be opened, and the pellets inside the capsule can be carefully dumped onto the applesauce for patients who have trouble swallowing capsules. 
• After combining the pellets and applesauce, immediately ingest the mixture.
• Use only cold applesauce that is soft enough to be taken without chewing. 
• You shouldn’t chew or shatter the pellets. It is not advised to keep the pellet/applesauce mixture for later usage. 
• Esomeprazole can be taken with antacids.

Storage Conditions

Store at a temperature not exceeding 30°C in a dry place. Protect from light and moisture. Keep out of reach of children.