-5%
Vonoprazan, the active ingredient in Voniza, is a potassium-competitive acid blocker (P-CAB) that does not require activation in acidic environments. It works by reversibly and competitively inhibiting the H+, K+-ATPase enzyme in gastric parietal cells, thereby effectively suppressing gastric acid secretion. Its strong basicity allows it to remain active at the acid production site for an extended period, providing significant protection against upper gastrointestinal mucosal damage.
