-3%
Introduction
MIF is an anti progestational steroids class of drug used for medical termination of pregnancy. It works by blocking the action of progesterone, essential hormone for the growth of pregnancy. MIF is given alone or in combination with some other medi…Show more
Uses of MIF
- Medical abortion
Side effects of MIF
Common
- Nausea
- Vomiting
- Uterine cramps
- Diarrhea
- Infection following abortion
- Uterine bleeding
How to use MIF
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. MIF is to be taken with food.
How MIF works
MIF blocks the effects of progesterone, a natural female hormone which is needed for the pregnancy to sustain. Without this hormone, the lining of the uterus (womb) breaks down as it does during a menstrual period and stops the growth of the pregnanc…Show more
What if you forget to take MIF?
If you miss a dose of MIF, please consult your doctor.
Quick Tips
MIF helps in medical termination of pregnancy.
If you vomit within 45 minutes of taking the tablet, talk to your doctor immediately. You will need to take another tablet.
Take it only as prescribed by the doctor. Miscarriages, if incomplete, may result in serious medical complications leading to hospitalizatio…Show more
Be cautious while driving or doing anything that requires concentration as it can cause dizziness and sleepiness.
It does not affect fertility. Use contraception to avoid pregnancy.
Take it no later than 63 days after the first day of your last menstrual period.
Vaginal bleeding may or may not occur after taking this medicine. Inform your doctor immediately if excessive bleeding occurs or if you suff…Show more
Brief Description
Indication
Termination of pregnancy, Labour induction, Cervical softening and dilatation, Postcoital contraception.
Administration
May be taken with or without food. 200 mg PO once given by a healthcare provider in a clinic, medical office, or hospital followed 24-48 hr later by …Show more
Adult Dose
Pregnancy Termination Mifepristone: Indicated for the medical termination of intrauterine pregnancy through 70 days gestation in combination with mis…Show more
Contraindication
Confirmed or suspected ectopic pregnancy, chronic adrenal failure, concurrent long-term corticosteroid therapy, history of allergy to mifepristone, mi…Show more
Mode of Action
Mifepristone is a progesterone antagonist with antiglucocorticoid activity. It binds to the intracellular progesterone receptor where it competitively…Show more
Precaution
Patient w/ haemostatic disorders or anaemia; malnutrition. Patients taking strong CYP3A4 inhibitors (when used in the treatment of Cushing’s syndrome)…Show more
Side Effect
>10% Abdominal pain, cramping (96%),Uterine cramping (83%),Nausea (43-61%),Headache (2-31%),Vomiting (1-26%),Diarrhea (12-20%),Dizziness (1-12%) …Show more
Interaction
Increased serum levels w/ CYP3A4 inhibitors (e.g. ketoconazole, itraconazole, erythromycin). Decreased serum levels w/ CYP3A4 inducers (e.g. dexametha