-2%
Thyronor contains synthetic Levothyroxine (T4), which mimics the body’s natural thyroid hormone. In peripheral tissues, T4 is converted into Triiodothyronine (T3), the more active form. T4 binds mainly to Thyroxine-Binding Globulin (TBG), which prolongs its half-life by protecting it from metabolism and excretion.
Half-life of T4: 6–7 days (shortened in hyperthyroidism; prolonged in hypothyroidism).
Liver metabolism: Major site of hormone breakdown, with excretion via urine after conjugation.
Enterohepatic circulation helps maintain blood levels.
A once-daily dose maintains stable T3 levels due to the long half-life of T4.
Thyronor (Levothyroxine Sodium)
Therapeutic Class: Thyroid hormones and hormone replacement therapy
- Primary treatment for hypothyroidism of any origin (except during transient hypothyroidism recovery, such as in subacute thyroiditis).
- TSH suppression therapyis used in conditions like goiter, thyroid nodules, and post-treatment of thyroid cancer (surgical or radiological).
- Counteracts drug-induced goiter, e.g., from lithium therapy.
- Diagnostic use in TSH suppression tests.
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