-2%
Paricalcitol-
Chronic Kidney Disease (CKD) Stages 3 and 4: Uniplar capsules are prescribed for adults and pediatric patients aged 10 years to prevent and treat secondary hyperparathyroidism associated with CKD Stages 3 and 4.
Chronic Kidney Disease Stage 5: Uniplar capsules are also indicated for adults and pediatric patients (10 years and older) with CKD Stage 5 undergoing hemodialysis (HD) or peritoneal dialysis (PD) to manage secondary hyperparathyroidism.
Paricalcitol is a synthetic, active vitamin D2 analog of calcitriol. Preclinical and in vitro research has shown that its effects are mediated through binding to the vitamin D receptor (VDR), selectively activating vitamin D-responsive pathways. Both vitamin D and paricalcitol help lower parathyroid hormone (PTH) levels by inhibiting its synthesis and secretion.
