-5%
Tablet Manufacturer/Distributor: Square Pharmaceuticals Ltd. Generic Name: Candesartan Cilexetil 16 mg Tablet
Indications
Candesartan Cilexetil is indicated for hypertension, and heart failure with impaired left ventricular systolic function.
Dosage & Administration
Hypertension: initially 8 mg (hepatic impairment 2 mg, renal impairment or intravascular volume depletion 4 mg) once daily, increased if necessary at intervals of 4 weeks to max 32 mg once daily; usual maintenance dose 8 mg once daily.
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Heart failure: initially 4 mg once daily, increased at intervals of at least 2 weeks to target dose of 32 mg once daily or to max tolerated dose.
Side Effects
Side-effects are usually mild. Symptomatic hypotension including dizziness may occur, particularly in patients with intravascular volume depletion (e.g. those taking high dose diuretics). Hyperkalemia occurs occassionally; angioedema has also been reported with some angiotension II receptor antagonist. Also vertigo, headache; rarely hepatitis, blood disorders, hyponatraemia, back pain, arthralgia, myalgia, rash, urticaria, pruritous.
Pregnancy & Lactation
When pregnancy is detected, Candesartan Cilexetil should be discontinued as soon as possible. It should be used in lactation.
Precautions & Warnings
Candesartan should be used with caution in renal artery stenosis, aortic or mitral valve stenosis and in obstructive hypertropic cardiomyopathy. Monitoring of plasma-potassium concentration is advised, particularly in the elderly and in patients with renal impairment; lower initial doses may be appropriate in these patients.
Use in Special Populations
Use in pediatric: Safety and effectiveness in pediatric patients have not been established.
Storage Conditions
Store in a cool & dry place. Protect from light and moisture