-5%
Cilnidipine, the active ingredient in Cilvas, is a dihydropyridine calcium channel blocker. It works by:
- Inhibiting calcium ion influx in vascular smooth muscle cells, leading to vasodilation and reduced blood pressure.
- Blocking calcium entry in sympathetic nerve cells prevents excessive norepinephrine release, which helps in controlling heart rate reflexively after blood pressure reduction.
Hypertension refers to high blood pressure, a condition where excessive force from the blood pumped by the heart puts pressure on blood vessels. Over time, this increased pressure can damage blood vessels, leading to serious health complications.
Cilvas is prescribed for managing hypertension and providing end-organ protection. It is particularly beneficial for elderly patients and individuals with diabetes and albuminuria. Additionally, Cilvas is increasingly used in patients with chronic kidney disease.