-2%
Torasemide–
- Management of edema associated with cardiac, renal, and hepatic disorders
- Treatment of hypertension, either as monotherapy or in combination with other antihypertensive agents
Dytor 2.5 mg acts by inhibiting the Na⁺/K⁺/2Cl⁻ co-transporter in the thick ascending limb of the loop of Henle, primarily by interfering with chloride binding. This action reduces the reabsorption of sodium and chloride, leading to increased urinary excretion of sodium, chloride, and water.
The enhanced delivery of sodium to the distal renal tubule promotes potassium excretion through the sodium–potassium exchange mechanism, particularly in the presence of elevated aldosterone levels. Dytor does not significantly affect glomerular filtration rate, renal plasma flow, or acid–base balance.
Its antihypertensive effect is secondary to diuresis, resulting in reduced plasma volume, decreased cardiac output, and temporary lowering of blood pressure.