-2%
Cefuroxime Axetil + Clavulanic Acid
Therapeutic Class: Second-generation cephalosporin antibiotic (with beta-lactamase inhibitor)
Tablet: May be taken with or without food.
Cefuroxime acts by binding to penicillin-binding proteins (PBPs), which inhibit the final transpeptidation step in bacterial cell wall synthesis. This halts peptidoglycan formation, leading to bacterial cell death.
Clavulanic acid inhibits beta-lactamase enzymes that normally inactivate cefuroxime by hydrolyzing its β-lactam ring. The combination extends the antibacterial spectrum of cefuroxime, making it effective against many beta-lactamase–producing bacteria resistant to cephalosporins or penicillins.
This combination is used to treat infections caused by susceptible organisms, including:
- Pharyngitis and Tonsillitis
- Acute Otitis Media
- Sinusitis and Acute Maxillary Sinusitis
- Respiratory Tract Infections
- Skin and Skin Structure Infections
- Urinary Tract Infections
- Acute Bacterial Exacerbation of Chronic Bronchitis
- Secondary Infections of Acute Bronchitis
- Community-Acquired Pneumonia
- Multi-Drug Resistant (MDR) Typhoid Fever
- Lyme Disease
- Surgical Prophylaxis
