-5%
Flunarizine, the active ingredient in Flurizin, is a selective calcium channel blocker and a difluorinated derivative of cinnarizine. It works by reducing excessive calcium influx into cells, preventing calcium overload while maintaining normal calcium homeostasis. Flunarizine also exhibits antihistaminic and sedative properties. It binds extensively to plasma proteins (99%).
Flurizin is prescribed for:
- Migraine prevention, including both classic migraines (with aura) and common migraines (without aura).
- Vestibular vertigo, when caused by a diagnosed functional disorder of the vestibular system.
- Peripheral Vascular Disease (PVD).
- Motion sickness.
- Refractory epilepsy, which does not respond to conventional antiepileptic treatment.