-2%
Alunib 180mg Tablet is prescribed for adults with non-small cell lung cancer (NSCLC).
- Specifically indicated for NSCLC with a particular type of abnormal gene called anaplastic lymphoma kinase (ALK).
When a person breathes in, the lungs absorb oxygen from the air and transport it into the bloodstream for distribution throughout the body. As the body’s cells utilize oxygen, they release carbon dioxide, which is carried back to the lungs by the bloodstream and expelled from the body during exhalation.
The lungs consist of various cell types, with epithelial cells being the predominant ones. Epithelial cells line the airways and produce mucus, serving to lubricate and protect the lungs. Additionally, the lungs contain nerve cells, hormone-producing cells, blood cells, and structural or supporting cells.
Regarding non-small cell lung cancer (NSCLC), there are two primary classifications of lung cancer, the other being small cell lung cancer, each requiring different treatment approaches. NSCLC originates when healthy lung cells undergo abnormal growth, forming a mass known as a tumor, lesion, or nodule. These growths can be either benign or cancerous. Cancerous lung tumors may shed cells that travel through the bloodstream or lymphatic fluid, potentially leading to metastasis in lymph nodes or distant parts of the body.
NSCLC comprises different subtypes, and understanding the specific type is crucial for determining appropriate treatment strategies. The classification is based on microscopic examination and the cell origin of the cancer. The main types of NSCLC include:
- Adenocarcinoma: Originating in epithelial cells lining the outer lungs that produce mucus, this is the most common type, accounting for approximately 40% of NSCLC cases.
- Squamous cell carcinoma: Arising from flat cells lining the lung’s interior, known as squamous cells, this type constitutes around 30% of NSCLC cases.
- Large cell carcinoma: Characterized by large cells that differ from adenocarcinoma or squamous cell carcinoma, this is the least common NSCLC type. Advances in diagnostic tools may reclassify some cases as adenocarcinoma or squamous cell carcinoma.
NSCLC-NOS (not otherwise specified) or NSCLC undifferentiated: In certain instances, determining the specific NSCLC subtype remains challenging even after testing.