Anxionil

Indications of Anxionil Tablet

Bromazepam is prescribed in-

Emotional problems, such as severe stress and worry. Difficulties making eye contact. Insomnia, agitation, anxiety, and agitated depressed responses

Pseudoangina pectoris, pericardial anxiety, tachycardia, monogenic hypertension, dyspnea, and hyperventilation are examples of functional abnormalities in the cardiovascular and respiratory systems.

Irritable bowel syndrome, epigastric discomfort, spasm, bloating, diarrhea, and other gastrointestinal disturbances

Urinary tract disturbances, such as frequency, irritable bladder, and dysmenorrhea.

Psychogenic headaches, asthma, and gastric and duodenal ulcers are examples of psychosomatic disorders.

It is also used to treat emotional responses to chronic organic illness.

Pharmacology of Anxionil Tablet

Bromazepam is a very effective psychotropic medication. It selectively lowers stress and anxiety at lower doses. It has sedative and muscle-relaxant effects at larger doses. Bromazepam binds to the GABA-A receptor, causing it to alter its shape and amplifying its inhibitory effects. Other neurotransmitters are unaffected.

Dosage of Anxionil Tablet

Standard dosage: Average dosage for outpatient therapy is 1.5-3 mg up to three times daily. Treatment of outpatients should begin with low doses, gradually increasing to the optimum level.

In severe cases, especially in hospital: 6-12 mg 2 or 3 times daily. The overall treatment generally should not be more than 8-12 weeks. In certain cases extension beyond the maximum treatment period may be necessary; if so, it should be taken with a re-evaluation of the patient’s status with special expertise.

Elderly and debilitated patients: Elderly patients and those with impaired hepatic functions require lower doses.

Children: Bromazepam is usually not indicated in children, but if the physician feels bromazepam treatment is appropriate, then the dose should be adjusted to their low body weight (about 0.1-0.3 mg/kg body weight)

Administration

Bromazepam tablets are for oral administration

Interaction of Anxionil Tablet

Bromazepam’s sedative effects may be increased when coupled with other centrally active medications. Antidepressants, hypnotics, opioids, antipsychotics, sedatives, antiepileptic medicines, sedative antihistamines, and anesthetics are examples of these medications. Cimetidine co-administration may increase the elimination half-life of bromazepam. Bromazepam should not be used with alcohol because the sedative effect of bromazepam may be exacerbated by alcohol.

Contraindications

Bromazepam is not recommended for individuals who have a history of hypersensitivity to the drug, severe respiratory insufficiency, severe hepatic insufficiency, or sleep apnea syndrome.

Side Effects of Anxionil Tablet

Tiredness, sleepiness, muscular weakness, numbed muscle, decreased alertness, confusion, headache, ataxia, and other common side effects include fatigue, drowsiness, muscle weakness, numbed muscle, reduced alertness, confusion, headache, ataxia, and so on. These side effects are most common at the start of therapy and generally go away after a while. Anterograde amnesia may develop when therapeutic dosages are used.

Pregnancy & Lactation

Bromazepam’s safety during pregnancy has not been verified. Because bromazepam is secreted in breast milk, it should be avoided during pregnancy and breastfeeding.

Precautions & Warnings

The usage of benzodiazepines and benzodiazepine-like substances may result in physical and psychological dependency on these drugs. This dependency is the dosage and treatment-length-dependent; it is also more prevalent in susceptible patients with a history of alcoholism. Once physical dependency has been established, discontinuing therapy will result in withdrawal symptoms. Headache, muscular discomfort, severe anxiety, tension, disorientation, and irritability are some of the symptoms. Because the danger of withdrawal and rebound symptoms increases with sudden termination of therapy, it is suggested that the dosage be gradually reduced. Bromazepam is not indicated as a first-line therapy for insomnia induced by psychotic disease. Driving a car or using machinery should be done with caution.

Storage Conditions

Keep away from light and heat in a dry area. Keep out of children’s reach.