Azmasol Bexicap Capsule (30pcs Box)

Indications

Salbutamol Inhaler is indicated for the treatment of reversible airway obstruction brought on by bronchitis and emphysema as well as for the treatment of bronchospasm in bronchial asthma.

Exercise-Induced Bronchospasm: Salbutamol Inhaler can be used to treat acute dyspnea attacks and can also be used as a preventative measure before physical activity or to stop exercise-induced asthma.

Pharmacology

The 2-adrenoceptor is a selective agonist of salbutamol. It has therapeutic effects on the 1-adrenoceptors of cardiac muscle but little to no effect on the 2-adrenoceptors of bronchial smooth muscle. Salbutamol causes short-acting (4-6 hours) bronchodilation with a rapid onset in reversible airway obstruction (within 5 minutes). By acting as an anti-inflammatory on mast cells, it also prevents the release of bronchoconstrictor mediators like histamine, neutrophil chemotactic factor (NCF), and prostaglandin D2.

Dosage & Administration

Administer Salbutamol Inhaler by oral inhalation only. Shake Salbutamol Inhaler well before each spray.

For relief of acute episodes of bronchospasm:

• Adults: As needed, take 1 or 2 puffs. The maximum dosage is eight puffs in a 24-hour period.
• Half the adult dose for children.

To avoid bronchospasm brought on by allergens or exercise:

• Adults: Two puffs 15 minutes before exercise or allergen exposure. Up to 4 times per day, a maximum dose of 2 puffs is allowed.
• Half the adult dose for children.

Chronic treatment:

• Adults: Two puffs of up to 200 mcg four times per day.
• Up to 200 mcg (2 puffs) four times per day for children.

Interaction

Salbutamol and non-selective beta-blocking drugs such as propranolol should generally not be prescribed together. Potentially serious hypokalaemia may result from β2-agonist therapy. Particular caution is advised in acute severe asthma as this effect may be potentiated by concomitant treatment with xanthine derivatives, steroids, diuretics, and hypoxia. It is recommended that serum potassium levels are monitored in such situations.

Contraindications

Salbutamol inhaler is contraindicated in patients with a history of hypersensitivity to salbutamol or any other components of Salbutamol inhaler.

Side Effects

Salbutamol is easily tolerated by most people. During inhalation, just a few adverse effects have been recorded. Tremors, anxiety, muscle cramps, headache, palpitation, a compensatory slight rise in heart rate, cardiac arrhythmias (including atrial fibrillation, supraventricular tachycardia, and extrasystoles), and tachycardia are all possible symptoms. Salbutamol inhalation can cause mouth and throat discomfort.

Pregnancy & Lactation

Pregnancy Classification C. In pregnant women, there are no sufficient and well-controlled studies using salbutamol inhalers or salbutamol sulfate. During pregnancy, this inhaler should only be used if the possible benefit outweighs the potential risk to the fetus. The components of the Salbutamol inhaler are not known to be excreted in human milk. When administering this inhaler to a nursing mother, exercise caution.

Precautions & Warnings

• The inhalers are known as “reliever” inhalers because they quickly alleviate breathing issues.
• When administering the medication and loading the dose, the inhaler must always be kept upright.
• After inhaling, if you taste a faintly sweet powder, you have taken the prescribed dose and the active ingredient has reached your lungs.
• Once you’ve used the inhaler, always replace the cap.
• In order to prevent any fungal infections in your mouth and throat, gargle with warm water after each inhalation.
• Among the side effects is possible to dry mouth. Regular mouthwash, good oral hygiene, more water consumption, and sugarless candy may be beneficial.
• If you require Azmasol HFA more than three times per week, it may indicate that your breathing issue is not under good control. Consult your physician about it.
• If you experience chest pain, a headache, or a racing heartbeat, let your doctor know right away.

Storage Conditions

Protect from light and moisture by storing in a cool, dry place below 30°C. Keep out of children’s reach.