-5%
Betabis contains bisoprolol fumarate, a beta-blocker used to manage:
- High blood pressure (hypertension)
- Angina (chest pain caused by heart disease)
- Moderate to severe heart failure
It is not intended for the emergency treatment of severely elevated blood pressure (hypertensive crisis).
Bisoprolol selectively blocks β1-adrenergic receptors, which are located mainly in the heart. This action slows the heart rate and reduces the workload of the heart, allowing it to pump blood more efficiently. As a result, blood pressure decreases, and symptoms of certain heart conditions improve.
Bisoprolol is highly selective for β1 receptors and has minimal effects on β2 receptors. Unlike some non-selective beta-blockers, long-term use does not significantly alter cholesterol levels, including beneficial HDL cholesterol.
The drug is well absorbed after oral administration, with an absolute bioavailability of approximately 88%. Food does not significantly affect absorption. Bisoprolol is eliminated through both the kidneys and the liver, and its half-life is approximately 10–12 hours, supporting once-daily dosing
