-5%
Bisocor, containing Bisoprolol Hemifumarate, is prescribed for hypertension, angina, and moderate to severe heart failure. It is not suitable for emergency treatment of hypertensive crises. Bisoprolol is highly selective for ß1 adrenergic receptors in the heart and vascular smooth muscle, reducing heart rate and blood pressure without adversely affecting lipid profiles. Its pharmacokinetic profile supports once-daily dosing with minimal variability in plasma concentration. The medication is well-absorbed orally, has a low first-pass effect, and is primarily eliminated via the kidneys after metabolism. Dosage should be adjusted based on individual patient needs, with caution in hepatic or renal impairment. Bisocor is contraindicated in certain conditions like cardiogenic shock and severe heart block. Potential side effects include fatigue, dizziness, and gastrointestinal disturbances. Special caution is advised during pregnancy and lactation. Bisocor should not be combined with other beta-blockers and requires careful management when used with certain antihypertensive or antiarrhythmic agents due to potential interactions.