-5%
Generic Name: Dexlansoprazole 60mgÂ
Manufacturer Name: Incepta Pharmaceuticals Limited
Indications of Delanix Capsule
Delanix 60 is a medication that lessens the quantity of acid your stomach produces. It is used to treat diseases of the stomach and intestine caused by excessive acid production, including heartburn, acid reflux, peptic ulcer disease, and some other conditions of the stomach. Delanix 60 is also used to stop the acidity and stomach ulcers that may result from using painkillers for an extended period of time. It is a member of the proton pump inhibitors class of drugs (PPIs).
Pharmacology of Delanix Capsule
A proton pump inhibitor (PPI), such as the sustained-release capsule of dexlansoprazole, prevents the secretion of gastric acid by specifically inhibiting (H + / K +) ATPase in gastric parietal cells. Dexlansoprazole stops the final stage of acid production by only affecting the proton pump. It is lansoprazole’s enantiomer (a racemic mixture of R and the enantiomer). In an oral capsule, dexlansoprazole is offered in a dual delayed release (DDR) formulation. Two different enteric-coated granule types with various pH-dependent dissolution profiles are mixed together in the capsule. Dexlansoprazole’s dual delayed-release formulation has two distinct peak plasma concentration-time profiles, with the first peak occurring 1 to 2 hours after administration and the second peak occurring 4 to 5 hours later. Dexlansoprazole’s mean Cmax and AUC values after oral administration rise roughly in proportion to the dose. The liver extensively metabolizes dexlansoprazole, which is then excreted in the urine.
Delanix Capsule Dosage & Administration
Dexlansoprazole dosing recommendations-
- Heartburn relief and maintenance of healed erosive esophagitis: 30 mgÂ
- Symptomatic, non-erosive GERD: 30 mg once daily every day for four weeks.
- 60 mg for the treatment of erosive esophagitis every day for as long as 8 weeks
Interactions
Drugs used: atazanavir, warfarin, tacrolimus, clopidogrel and methotrexate. With food and others: no data available.
Contraindications
Patients who are known to be allergic to any component of the preparation should not use dexlansoprazole.
Side Effects
Common side effects: diarrhea, abdominal pain, nausea, vomiting, and flatulence.
Pregnancy
Pregnancy category B. There are no adequate and well-controlled studies on the use of dexlansoprazole in pregnant women. There are no adequate and well-controlled studies on the use of dexlansoprazole in breastfeeding mothers.
Precautions
Gastric neoplasms, Clostridium difficile-related diarrhea, fractures, hypomagnesemia, and simultaneous use of dexlansoprazole and methotrexate.
Storage Conditions
Store below 30°C temperature & in a dry place, protected from light. Keep all medicines out of reach of children.