Docopa Syrup 60ml

Indications of Docopa 60 ml

Docopa is used to treat and prevent asthma and chronic obstructive pulmonary disease symptoms (a lung disorder in which the flow of air to the lung is blocked). It aids in relaxing the muscles of the airways, widening them, and making breathing easier. Docopa can be consumed with food in the evening. To get the most out of it, take it at the same time every day. The dose and frequency of administration are determined by the purpose of the medication. Your doctor will determine how much treatment you require to alleviate your symptoms.

Pharmacology

Doxophylline is a relatively new bronchodilator. The presence of a dioxolane group in position 7 distinguishes it structurally from Theophylline. Doxophylline relaxes bronchial smooth muscle by specifically inhibiting phosphodiesterase 4. Doxophylline appears to have a lower affinity for adenosine e A1 and A2 receptors than Theophylline, which may account for the drug’s improved safety profile. Doxophylline has been shown to inhibit the product platelet-activating factor (PAF) as well as the formation of leukotrienes.

Dosage and Administration

• Elderly: Take a 200 mg tablet two or three times per day.
• Adults: Take one 400 mg tablet two or three times per day, or as directed by a doctor.
• Children: >12 years old: 10 mL syrup or 200 mg tablet two or three times per day.
• 6-12 years old: 6-9 mg/kg body weight twice daily; if body weight is 10 kg, 3 ml (60 mg) twice daily or as prescribed by the physician.
• Doxophylline SR tablet is to be taken once daily or as prescribed by the physician if the required daily dose of Doxophylline is 400 mg.

Interaction of Docopa 60 ml

Doxophylline shouldn’t be taken at the same time as any other xanthine derivatives. Ephedrine and xanthine have been demonstrated to interact negatively. Oleandomycin, lincomycin, clindamycin, allopurinol, cimetidine, ranitidine, propranolol, and the influenza vaccine are examples of medications that, along with another xanthine, may impair the liver’s ability to eliminate xanthine, raising blood levels. There is no evidence to suggest a connection between adverse events and doxophylline blood concentrations.

Contraindications

Doxophylline is not advised during a myocardial infarction that is acute. It is also not recommended for use by those who have hypotension, nursing mothers, and individuals who have displayed an allergy to its ingredients.

Side Effects of Docopa 60 ml

Doxophylline rarely causes serious side effects, however possible side effects are similar to taking an excessive amount of caffeine. These include nausea, vomiting, headache, upset stomach, and heartburn.

Pregnancy & Lactation

Animal reproduction studies demonstrate that doxophylline does not impair fertility or harm fetuses when administered to pregnant animals. However, due to the limited human experience with xanthine during pregnancy, pregnant women should only get them in an emergency. Breastfeeding women should not use doxophylline.

Precautions & Warnings

• The half-life of xanthine derivatives is influenced by a number of recognized factors.
• A delay might occur in patients with liver disease, congestive heart failure, and those using specific medications like erythromycin, oleandomycin, lincomycin, allopurinol, cimetidine, propranolol, and the influenza vaccination.
• In these situations, a lower dose of doxophylline can be necessary.
• Avoid Docopa with caffeine and chocolate as well as food containing caffeine and chocolate such as tea leaves, and cocoa beans.
• If you have a history of smoking or if you have ever received a diagnosis of kidney, liver, or heart disease. You might need to change your dose. Inform your physician.
• An increase in clearance and a reduction in the mean half-life may be brought on by smoking, phenytoin, and other anticonvulsants. Greater Doxophylline doses may be necessary for these conditions.

Storage Conditions

Keep in a dry place away from light and heat. Keep out of the reach of children. Doxophylline should be used only on the prescription of a specialist physician.n.