-5%
Domperidone is a dopamine antagonist that primarily blocks dopamine receptors in the Chemoreceptor Trigger Zone (CTZ) and the stomach. Its prokinetic action stems from its ability to inhibit dopamine’s influence on gastrointestinal motility.
- Enhances gastric emptying
- Promotes antral and duodenal peristalsis
- Regulates pyloric contraction
- Increases esophageal peristalsis and lower esophageal sphincter pressure, reducing regurgitation
Blood-Brain Barrier: Due to minimal penetration, Domperidone rarely causes neurological side effects.
Domilux is prescribed for various gastrointestinal and neurological conditions, including:
Dyspeptic Symptoms associated with delayed gastric emptying, gastroesophageal reflux, and esophagitis, such as:
- Epigastric fullness and abdominal distension
- Upper abdominal pain
- Belching and flatulence
- Early satiety
- Nausea and vomiting
- Heartburn, with or without gastric regurgitation
- Non-ulcer dyspepsia
- Acute Nausea & Vomiting due to functional, organic, infectious, dietary causes, or induced by radiotherapy, drug therapy, or migraine.
- Parkinson’s Disease: Management of nausea and vomiting caused by dopamine agonists.
- Radiological Studies: Used to accelerate barium transit during radiological assessments.
📌 Use only under the supervision of a registered physician.