-5%
Empatab M ER tablets are prescribed for adults with type 2 diabetes mellitus as an addition to diet and exercise in the following cases:
- Patients who do not achieve sufficient glycemic control on their maximum tolerated dose of Metformin alone.
- Patients requiring combination therapy with other antidiabetic medications when Metformin alone is insufficient.
- Patients already taking separate tablets of Empagliflozin and Metformin.
Empagliflozin is an SGLT2 (Sodium-Glucose Co-Transporter 2) inhibitor. SGLT2 is the key transporter responsible for reabsorbing glucose in the kidneys. By blocking SGLT2, Empagliflozin reduces glucose reabsorption, lowers the renal threshold for glucose, and increases urinary glucose excretion.
Metformin Hydrochloride is a biguanide-class oral antihyperglycemic drug that helps manage type 2 diabetes. It effectively lowers both fasting and postprandial blood glucose levels without causing hypoglycemia. Metformin works by reducing hepatic glucose production, decreasing glucose absorption in the intestines, and improving insulin sensitivity through enhanced peripheral glucose uptake and utilization.