-5%
Metronidazole, an imidazole derivative, is a potent antiprotozoal and antibacterial agent. Its 5-nitro group undergoes enzymatic reduction by anaerobic organisms, producing reactive intermediates that disrupt microbial DNA, ultimately exerting a bactericidal effect.
Flagyl is used in the treatment and prevention of infections caused by anaerobic bacteria and certain protozoa. These include:
- Prevention of post-surgical infections caused by anaerobes (especially Bacteroides and anaerobic streptococci).
- Treatment of conditions such as septicaemia, bacteraemia, peritonitis, brain and pelvic abscesses, pelvic cellulitis, and infected surgical wounds caused by anaerobic organisms.
- Management of urogenital trichomoniasis.
- Treatment of bacterial vaginosis (non-specific vaginitis).
- All forms of amoebiasis: intestinal, extra-intestinal, and asymptomatic cyst carriers.
- Treatment of Giardiasis.
- Acute ulcerative gingivitis.
- Anaerobically infected leg ulcers and bedsores.
- Acute dental infections due to anaerobic pathogens.
- Antibiotic-associated pseudomembranous colitis.