-5%
Gefapixant 45 mg | Indicated for Refractory or Unexplained Chronic Cough in Adults
Gefapix is prescribed for adult patients suffering from either refractory chronic cough or unexplained chronic cough when other underlying causes have been ruled out.
Gefapixant is a selective P2X3 receptor antagonist, which targets ATP-sensitive ion channels located on C-fibers of the vagus nerve in the respiratory tract. These fibers are activated during inflammation or chemical irritation, leading to the release of ATP, which triggers a cough reflex. By inhibiting ATP from binding to these receptors, Gefapixant reduces the cough signal and alleviates chronic coughing.