-2%
Lefamulin Acetate is a semi-synthetic pleuromutilin antibacterial agent available in oral and IV forms. It acts by inhibiting bacterial protein synthesis through strong binding at the peptidyl transferase center (PTC) of the 23S rRNA in the 50S ribosomal subunit. This unique binding prevents bacterial growth, including resistant strains associated with pneumonia.
- Lefabac is prescribed for adults with community-acquired bacterial pneumonia (CABP) caused by susceptible strains of:
- Streptococcus pneumoniae
- Staphylococcus aureus (methicillin-susceptible isolates)
- Haemophilus influenzae
- Legionella pneumophila
- Mycoplasma pneumoniae
- Chlamydophila pneumoniae