Levoxin Eye Drops 5ml

Indications

Levofloxacin eye drops are used to treat bacterial conjunctivitis caused by the following microorganisms:

• Gram-Positive Aerobic Bacteria-
• Corynebacterium spp.
• Oureus Staphylococcus
• The bacteria Staphylococcus epidermidis
• Pneumococcus pneumonia
• Streptococcus (C/F Groups)
• Streptococcus (Group G) (Group G)
• Group Streptococcus virions
• Gram-negative bacteria-
• Iwoffii Acinetobocter
• The bacteria Haemophilus influenzae
• Marcescent Serratia
• Levofloxacin is also being studied as a potential treatment for a variety of ocular diseases, including bacterial corneal ulcers, blepharitis, hordeolum, and perioperative conditions.

Pharmacology

Levofloxacin eye drops in a sterile topical ophthalmic solution. It is a third-generation synthetic fluoroquinolone bactericidal antibiotic with broad activity against Gram-positive and Gram-negative ocular infections. It prevents DNA replication, transcription, repair, and recombination by inhibiting the enzymes bacterial topoisomerase IV and DNA gyrase.

Dosage

Adults and children 1 year of age and older: 0.5% eye drop:

• Instill 1-2 drops in the affected eye(s) every 2 hours while awake, up to 8 times per day on days 1 and 2.
• Days 3–7: Apply 1-2 drops to the affected eye(s) every 4 hours while awake, up to 4 times per day.

Adults and children aged 6 and up: 1.5% eye drop:

• Days 1–3: Apply one to two drops to the affected eye(s) every 30 minutes to 2 hours while awake and every 4 to 6 hours after retiring.
• Day 4 and onwards: Instill one to two drops in the affected eye(s) every 1 to 4 hours while awake.

1-year-old children: The safety and effectiveness of Levofloxacin in children under the age of one year have not been established.

Administration

• You’ve been given Levoxin to treat bacterial infections in your eyes.
• Even if you feel better, do not skip any doses and complete the entire course of treatment.
• Immediately after instilling the medication, apply pressure to the corner of the eye (close to the nose) for about 1 minute.
• To avoid contamination, avoid touching the tip to any surface or your eye.
• To avoid dilution, wait at least 5-10 minutes before administering the next medication in the same eye.
• When first used, it may cause temporary blurring of vision. Use caution when driving or operating machinery.
• Wearing contact lenses is not recommended until your infection has cleared up.
• Use the medication within 4 weeks of opening it.

Interaction

There have been no specific drug interaction studies with levofloxacin eye drops. Systemic administration of certain quinolones, on the other hand, has been shown to increase plasma theophylline concentrations, interfere with caffeine metabolism, and improve the effects of the oral anticoagulant warfarin and its derivatives.

Contraindications

It is not recommended for individuals who have a history of hypersensitivity to Levofloxacin, other quinolones, or any of the medication’s components.

Side Effects

Only about 1-3 percent of people experienced side effects such as temporary impaired vision, fever, foreign body sensation, headache, transient ocular burning, ocular pain or discomfort, pharyngitis, and photophobia. Less than 1% of patients experienced allergic reactions, lid edema, ocular dryness, or ocular irritation.

Pregnancy & Lactation

Pregnancy Type C. Only if the possible benefit outweighs the potential danger to the fetus should levofloxacin be taken during pregnancy. Levofloxacin levels in human milk have not been determined. When administering Levofloxacin eye drops to a nursing mother, extreme caution should be used.

Precautions & Warnings

Long-term usage may result in the overgrowth of non-susceptible organisms, such as fungi. If superinfection arises, stop using the product and seek alternate treatment.

Storage Conditions

Keep eye drops away from light, in a cold (15°-25° C) and dry area, and out of the reach of children.