-5%
Atorvastatin belongs to the statin class of medicines and works by blocking the enzyme HMG-CoA reductase, which is essential for cholesterol production in the liver. This action lowers cholesterol synthesis and increases the liver’s ability to remove LDL cholesterol from the bloodstream.
Liptor (Atorvastatin) is a cholesterol-lowering medication used alongside dietary and lifestyle modifications when non-drug measures alone are insufficient. It helps reduce elevated levels of total cholesterol, LDL (“bad”) cholesterol, apolipoprotein B (Apo-B), and triglycerides. It is prescribed for conditions such as familial hypercholesterolemia, mixed dyslipidemia, hypertriglyceridemia, dysbetalipoproteinemia, and to lower the risk of cardiovascular events in individuals with coronary artery disease. It is also beneficial for patients whose cholesterol levels are increased due to diabetes or kidney transplantation.
- Rapidly absorbed after oral administration, with peak blood levels reached within 1–2 hours.
- About 14% of the drug is available in the bloodstream after absorption.
- Highly bound to plasma proteins (approximately 98%).
- Metabolized primarily in the liver through the CYP3A4 enzyme system.
- Eliminated mainly through bile, with a plasma half-life of about 14 hours.
- Less than 2% is excreted through urine.