Lyca 50mg Capsule 10pcs
Lyca 50mg Capsule 10pcs Original price was: 100.00৳ .Current price is: 95.00৳ .
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Lyca CR 165 mg
Lyca CR 165 mg Original price was: 200.00৳ .Current price is: 190.00৳ .
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Lyca 75mg Capsule 1 Strip

SKU: 5407

Manufacturer: Delta Pharma Limited

Generic: Pregabalin

Type: Capsule

Pack Size: 10 Pcs

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Original price was: 150.00৳ .Current price is: 142.50৳ .

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Description

Pregabalin is a chemical analogue of the inhibitory neurotransmitter GABA, but it does not directly bind to GABA or benzodiazepine receptors. Instead, it strongly attaches to the alpha2-delta subunit of voltage-gated calcium channels in the CNS. This binding is thought to mediate its pain-relieving and anti-seizure effects, although the complete mechanism is not fully understood.

Diabetic Neuropathic Pain (Adults)

IR Tablets: Start with 50 mg thrice daily (150 mg/day). Can be increased to 100 mg thrice daily (300 mg/day) as tolerated.

CR Tablets: Start at 165 mg once daily after an evening meal; may be increased to 330 mg/day within 1 week. Max: 330 mg/day.

Postherpetic Neuralgia (Adults)

IR Tablets: Begin with 75 mg twice daily or 50 mg three times daily. Dose can increase to 300 mg/day in 1 week. If inadequate relief after 2–4 weeks, may go up to 600 mg/day.

CR Tablets: Start at 165 mg once daily, increase to 330 mg once daily. If still insufficient, may go up to 660 mg/day, but only in those who tolerate 330 mg/day well.

Fibromyalgia (Adults)

Start with 75 mg twice daily (150 mg/day). May be raised to 150 mg twice daily (300 mg/day). If needed, can go up to 225 mg twice daily (450 mg/day).

Spinal Cord Injury-Related Neuropathic Pain (Adults)

Initial: 75 mg twice daily. May increase to 150 mg twice daily (300 mg/day) after 1 week. Up to 600 mg/day may be used if well tolerated and needed.

Switching from IR to CR Tablets

Match daily IR dose to the nearest CR dose (e.g., 150 mg IR → 165 mg CR).

Begin CR dosing in the evening after taking the final morning dose of IR.

Missed CR Dose

If missed after dinner, Take before bed with a snack.

If missed at bedtime: Take with breakfast the next day.

If missed after breakfast: Resume next scheduled evening dose.

  • Pediatric Patients: Safety not established for most indications except partial seizures in those ≥1 month.
  • Extended-release tablets: Not recommended for pediatric patients.

Pregabalin CR tablets must be swallowed whole and taken after an evening meal. Do not split, crush, or chew.
📌 Gradually discontinue over at least 1 week.