-5%
Mirogabalin besylate is used for the treatment of:
- Neuropathic pain
- Diabetic peripheral neuropathic pain (DPNP)
- Postherpetic neuralgia (PHN)
- Peripheral neuropathic pain (PNP)
Mirogabalin selectively binds with high affinity to the α2δ subunits of voltage-gated calcium channels (VGCCs). This action reduces calcium influx into nerve cells, thereby decreasing neurotransmitter release in dorsal root ganglion (DRG) neurons and helping to relieve neuropathic pain.
- Mirogabalin may cause dizziness, drowsiness, or loss of consciousness; avoid driving or operating machinery
- Use with caution in elderly patients
- May lead to weight gain
- Can cause blurred or double vision
