Napa Suppository 125mg 5pcs

Indications

Fever, common cold, influenza, headache, toothache, earache, body ache, myalgia, neuralgia, dysmenorrhoea, sprains, colic pain, back pain, post-operative pain, postpartum discomfort, inflammatory pain, and post-vaccination pain in children are among the conditions for which paracetamol is prescribed. It’s also used to treat rheumatic and osteoarthritic pain, as well as joint stiffness.

Pharmacology

Paracetamol is an analgesic and antipyretic with just a little anti-inflammatory effect. Paracetamol (Acetaminophen) is considered to work largely in the central nervous system (CNS), raising the pain threshold by blocking both isoforms of the cyclooxygenase enzymes COX-1, COX-2, and COX-3, which are involved in prostaglandin (PG) production. Paracetamol is a para aminophenol derivative that possesses analgesic, antipyretic, and anti-inflammatory effects. One of the most commonly used, safest, and fastest-acting analgesics is paracetamol. It is well tolerated and devoid of aspirin’s numerous adverse effects.

Dosage & Administration

Suppository:

• Children aged 3 to 12 months: 60-120 mg four times per day.
• Children aged 1 to 5 years: 125-250 mg 4 times per day.
• Children aged 6 to 12 years: 250-500 mg four times per day.
• Adults and children over the age of 12: 0.5-1 gm four times daily

Interaction

Barbiturates, tricyclic antidepressants, and alcohol may impair the capacity of patients to metabolize large doses of paracetamol. Overdosing paracetamol can cause hepatotoxicity if used with alcohol. Anticonvulsants and oral steroid contraceptives cause liver enzymes to increase, which may prevent therapeutic Paracetamol levels from being reached by increasing first-pass metabolism or clearance.

Contraindications

It is contraindicated in known hypersensitivity to Paracetamol.

Side Effects

Although hematological responses such as thrombocytopenia, leucopenia, pancytopenia, neutropenia, and agranulocytosis have been described, paracetamol’s side effects are typically moderate. Pancreatitis, rashes, and other allergic responses can happen at any time.

Pregnancy & Lactation

It is not recommended if you have a known hypersensitivity to paracetamol.

Precautions & Warnings

• To avoid stomach upset, take Napa 125 Suppository with food or milk.
• Take it according to your doctor’s dosage and duration. Long-term use can result in serious side effects such as stomach bleeding and kidney problems.
• Take no indigestion medications (antacids) within two hours of using the Napa 125 Suppository.
• Alcohol should be avoided while taking this medication because it increases your risk of stomach problems.
• Patients with poor kidney or liver function should use paracetamol with care.
• Patients taking other medications that damage the liver should use caution when using paracetamol.

Storage Conditions

Keep below 30°C temperature in a dry place. Protected from light. Do not freeze. Keep out of reach of children.