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Navigo 40 Infusion | 40mg Vial

SKU: 2755

Manufacturer: Incepta Pharmaceuticals Ltd.

Generic: Nivolumab

Type: Injection

Pack Size: 1 Pc

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Original price was: 40,000.00৳ .Current price is: 39,200.00৳ .

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Description

Nivolumab is a human IgG4 monoclonal antibody that targets the PD-1 receptor on T-cells, disrupting its interaction with PD-L1 and PD-L2. This releases the immune inhibition mediated by the PD-1 pathway, enabling T-cells to recognize and destroy cancer cells. When combined with ipilimumab (a CTLA-4 inhibitor), it enhances T-cell activation, promoting a more potent anti-tumor response.

Navigo 40 (Nivolumab) is a PD-1 immune checkpoint inhibitor indicated for the treatment of various cancers, including:

  • Non-small cell lung cancer (NSCLC)
  • Renal cell carcinoma (RCC)
  • Melanoma
  • Classical Hodgkin lymphoma (cHL)
  • Liver cancer (Hepatocellular carcinoma)
  • Head and neck squamous cell carcinoma (SCCHN)
  • Urothelial carcinoma
  • Esophageal and gastric cancers
  • Colorectal cancer with MSI-H or dMMR
  • Malignant pleural mesothelioma