-4%
Nitrocontin is used for the prevention of angina pectoris (chest pain due to heart-related causes). It is not suitable for the treatment of acute anginal attacks due to its delayed onset of action.
- Nitroglycerin exerts its effect by relaxing vascular smooth muscles, leading to vasodilation of both arteries and veins.
- Venous dilation reduces venous return to the heart, lowering preload and left ventricular end-diastolic pressure.
- Arterial dilation decreases systemic vascular resistance and afterload, reducing the heart’s oxygen demand.