-5%
Orthofit is recommended for the management and support of joint health, particularly in conditions such as:
- Osteoarthritis
- Rheumatoid arthritis
- Joint pain and inflammation
- Reduced flexibility and mobility
- Stiffness and discomfort in joints (especially during knee extension)
- Compromised joint function
- Joint stress due to intense physical activity or sports
Orthofit combines Glucosamine, Chondroitin, and Undenatured Type II Collagen, which work synergistically to maintain joint integrity and reduce inflammation.
Glucosamine is an amino sugar naturally present in cartilage, essential for synthesizing joint cartilage and maintaining joint structure.
Chondroitin is a mucopolysaccharide that promotes cartilage regeneration, inhibits enzymes that degrade cartilage, attracts fluid to cartilage cells, and aids in joint lubrication.
Undenatured Type II Collagen, derived from chicken sternum through a patented, low-temperature process, retains its triple-helix structure and biological activity. It works through a mechanism called oral tolerization, where it interacts with immune cells (Peyer’s patches) in the gut. This triggers the release of collagen-specific regulatory T-cells that travel to joint tissues to inhibit inflammatory T-cell responses.
These regulatory T-cells help:
- Suppress joint inflammation
- Inhibit collagenase (enzymes that degrade cartilage)
- Reduce inflammatory cytokines
- Preserve and regenerate cartilage, improving joint health and function