-5%
Pantoprazole is a proton pump inhibitor (PPI) that blocks the final step of gastric acid secretion by inhibiting the H+/K+ ATPase enzyme system in gastric parietal cells. It suppresses both basal and stimulated gastric acid production.
Pantoprazole is prescribed for the treatment of:
- Peptic ulcer disease (gastric and duodenal ulcers)
- Helicobacter pylori infection (in combination therapy)
- Gastroesophageal reflux disease (GERD)
- Zollinger-Ellison syndrome and other pathological hypersecretory conditions
- Oesophagitis
- Acid-related dyspepsia
- NSAID-associated ulceration
- Ulcers resistant to H2 receptor antagonists
- Gastrointestinal bleeding related to stress
- Prophylaxis of acid aspiration during induction of anesthesia
