-5%
Pantoprazole is a proton pump inhibitor (PPI) that suppresses gastric acid secretion by irreversibly binding to the H+/K+ ATPase enzyme system located on gastric parietal cells. This action blocks the final step of acid production and effectively reduces both basal and stimulated gastric acid secretion for more than 24 hours, regardless of the triggering stimulus.
Pantolok is indicated in conditions where suppression of gastric acid secretion is beneficial, including:
- Peptic ulcer disease
- Gastroesophageal reflux disease (GERD)
- NSAID-induced gastric or duodenal ulcers
- Eradication of Helicobacter pylori infection (in combination with antibiotics)
- Zollinger-Ellison syndrome and other hypersecretory conditions
