-5%
Renexin XR is indicated for the treatment of chronic angina (heart-related chest pain). It is used to prevent angina attacks, not to relieve acute episodes. The medication works by improving how the heart uses energy, making it function more efficiently.
- Take consistently at the same time each day
- Helps improve HbA1c and blood sugar in diabetic patients
- May cause drowsiness or dizziness—avoid driving until the effects are known
- Regular ECG monitoring is recommended, especially during dose initiation
- Maintain a heart-healthy lifestyle: quit smoking, reduce alcohol, manage stress
Ranolazine exerts anti-anginal and anti-ischemic effects by inhibiting the late phase of the inward sodium current in heart muscle cells. This results in:
- Decreased intracellular sodium and calcium overload
- Improved myocardial relaxation
- Restoration of ventricular pump function
- Reduced myocardial oxygen consumption
Notably, its effects are not dependent on lowering heart rate or blood pressure. QT interval prolongation occurs due to IKr (potassium current) inhibition, but without an increase in arrhythmic events at therapeutic doses.