-5%
Sintel (Albendazole)
Sintel is effective in both single and mixed infestations, including:
- Hookworm (Ancylostoma, Necator)
- Roundworm (Ascaris)
- Threadworm (Enterobius)
- Whipworm (Trichuris)
- Strongyloides
- Tapeworm
- Opisthorchis
- Hydatid disease
It is also used in giardiasis and other helminthic infections.
Sintel (Albendazole) is a broad-spectrum benzimidazole anthelmintic, highly effective against most nematodes and several cestodes. It possesses vermicidal, ovicidal, and larvicidal actions. Its primary mechanism involves inhibition of tubulin polymerization, which disrupts cytoplasmic microtubule formation, leading to impaired glucose uptake and eventual parasite death.
Pharmacology
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Contraindications
Neonates (not recommended).
Pregnant women (should be avoided; insufficient data on placental transfer).
Caution in children <10 kg (dose reduction may be considered).
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