-1%
Terbinafine kills fungi by blocking squalene epoxidase, an enzyme required for producing ergosterol, an essential component of fungal cell membranes. This damages the fungal cells and leads to their death.
- Complete the entire course of treatment.
- Fungal infections may take several weeks to clear completely.
- Nail infections can take several months for healthy nails to regrow.
- Avoid contact with eyes, nose, and mouth; rinse thoroughly with water if accidental exposure occurs.
- Use sunscreen and protective clothing when outdoors during treatment.
Terbikill 250 is an antifungal medicine used to treat fungal infections affecting the skin, nails, and scalp, including:
- Ringworm (Tinea corporis)
- Athlete’s foot (Tinea pedis)
- Jock itch (Tinea cruris)
- Nail fungal infections (Onychomycosis)
- Scalp fungal infections (Tinea capitis)
- Can be taken with or without food.
- Follow your doctor’s prescribed dose and duration.
Adult Dosage
Nail fungal infections:
- 250 mg once daily
- Fingernail infections: 6 weeks
- Toenail infections: 12 weeks
Skin fungal infections:
- 250 mg daily (single dose or divided doses)
- Tinea corporis and tinea cruris: 2–4 weeks
- Tinea pedis: 2–6 weeks
Pediatric Dosage (Tinea Capitis)
Children older than 4 years:
- Less than 25 kg: 125 mg daily for 6 weeks
- 25–35 kg: 187.5 mg daily for 6 weeks
- More than 35 kg: 250 mg daily for 6 weeks
Missed Dose
Take the missed dose as soon as you remember. If it is nearly time for the next dose, skip the missed dose and continue your regular schedule. Do not take two doses at the same time.
Common Side Effects
Topical use:
- Skin peeling
- Burning sensation
- Redness
- Itching
- Irritation at the application site
Oral use:
- Headache
- Rash
- Itching
- Nausea
- Diarrhea
- Indigestion
- Abdominal pain
- Changes in taste
- Elevated liver enzymes
- Mild visual disturbances
Serious Side Effects
Although rare, serious reactions may occur:
- Severe liver injury or liver failure
- Stevens-Johnson syndrome (severe skin reaction)
- Significant reduction in white blood cells (neutropenia)
Seek immediate medical attention if you develop severe rash, yellowing of the skin or eyes, dark urine, or persistent fever.
Who Should Not Use It
Terbikill 250 should not be used in people with:
- Allergy to terbinafine
- Active or chronic liver disease
- Breastfeeding mothers (oral therapy)
Precautions
- Use cautiously in patients with liver or kidney disease.
- Liver function tests may be required before and during oral treatment.
- Avoid unnecessary sun exposure because skin sensitivity to sunlight may increase.
- Inform your doctor if symptoms do not improve after 4 weeks of treatment.
Pregnancy and Breastfeeding
- Use during pregnancy only if clearly needed and advised by a doctor.
- Oral terbinafine passes into breast milk and is generally not recommended while breastfeeding.
Drug Interactions
Terbinafine may interact with:
- Medicines metabolized by CYP2D6 enzymes
- Rifampicin (may reduce terbinafine effectiveness)
- Cimetidine (may increase terbinafine levels)
Keep below 30°C, protected from light and moisture. Keep out of reach of children.