-2%
Fungal infections of the skin can be caused by various organisms. Some common culprits include Trichophyton species, such as T. rubrum, T. mentagrophytes, T. verrucosum, and T. violaceum. Other notable fungi include Microsporum canis and Epidermophyton floccosum. Additionally, yeast infections, particularly those stemming from the genus Candida (like C. albicans), are also prevalent. Another condition associated with fungal infection is Pityriasis (tinea) versicolor, caused by Pityrosporum orbicular, which is also referred to as Malassezia furfur.
- Terbinafine is indicated for:
- Treatment of fungal infections such as onychomycosis (fingernail and toenail infections).
- Dermatophytosis including tinea corporis, tinea cruris, and tinea pedis.
- Cutaneous candidiasis and pityriasis versicolor.
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Pharmacology:
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Dosage & Administration:
Terbinafine Tablets:
Fingernail onychomycosis: 250 mg once daily for 6 weeks.
Toenail onychomycosis: 250 mg once daily for 12 weeks.
Clinical improvement may take several months after the end of treatment as the healthy nail grows out.
Terbinafine Granules:
< 25 kg: 125 mg/day up to 6 weeks.
25–35 kg: 187.5 mg/day up to 6 weeks.
35 kg: 250 mg/day up to 6 weeks.