-5%
Meniere’s disease, tinnitus and/or progressive loss of hearing, vertigo, dizziness.
Administration
Should be taken with food.
Adult Dose
Adult: Initially, 8-16 mg tid. Maintenance: 24-48 mg daily.
Contraindication
Phaeochromocytoma. Porphyria.
Mode of Action
Betahistine improves the microcirculation in the labyrinth which reduces endolymphatic pressure.
Precaution
Active peptic ulcer, bronchial asthma, pregnancy and lactation.
Side Effect
Rash, pruritus, urticaria, dyspepsia, nausea, peptic ulcer disease, headache, dizziness, insomnia.
Interaction
May antagonise antihistamines. May decrease bronchodilator effects of beta-2 agonists.