-2%
Entecavir is a potent antiviral agent belonging to the nucleoside analogue class. It acts as a selective inhibitor of hepatitis B virus DNA polymerase, an enzyme essential for HBV replication.
After intracellular activation, entecavir inhibits:
- HBV DNA polymerase priming
- Reverse transcription of the negative DNA strand from pregenomic RNA
- Synthesis of the positive DNA strand
By blocking these critical steps, entecavir suppresses viral DNA synthesis and reduces HBV replication within infected liver cells.
- Take Vironex 1 on an empty stomach every day at the same time.
- Do not stop treatment without medical advice.
- Attend regular follow-up visits and blood tests.
- Avoid alcohol to reduce additional liver stress.
- Continue precautions to prevent transmission of hepatitis B.
- Report symptoms such as severe fatigue, jaundice, abdominal swelling, or breathing difficulties immediately.
Vironex 1 (Entecavir) is indicated for the treatment of chronic hepatitis B (CHB) infection caused by the hepatitis B virus (HBV). It is used in patients with evidence of active viral replication and signs of ongoing liver inflammation or damage, such as elevated liver enzymes (ALT/AST) or histologically active liver disease.
Entecavir helps suppress HBV replication, reducing viral load and slowing the progression of liver disease. It is not a cure for hepatitis B but can help prevent complications such as cirrhosis, liver failure, and hepatocellular carcinoma.