-5%
Olmesartan medoxomil, the active ingredient in Xyotil, is an angiotensin II receptor blocker (ARB).
- Angiotensin II, a potent vasoconstrictor, is blocked from binding to AT1 receptors in vascular smooth muscle.
- This action reduces vasoconstriction, aldosterone release, and renal sodium reabsorption, thereby lowering blood pressure.
- Unlike ACE inhibitors, Olmesartan does not affect bradykinin response, which minimizes the risk of cough.
