-5%
This combination supplement is used to address deficiencies in iron, folic acid, and zinc, often required during physiologically stressful conditions like pregnancy, lactation, and anemia. It provides essential nutrients for hemoglobin synthesis, erythropoiesis, and immune support.
- Treatment of Deficiencies:
- Iron deficiency anemia
- Folic acid and zinc deficiencies
- Prophylaxis:
- Preventing iron and zinc deficiency during pregnancy and lactation
- Dietary supplementation when nutrient intake is insufficient
Ferrous Ascorbate (Iron + Ascorbic Acid)
- Structure and Stability:
- Ferrous ascorbate is a stable complex combining iron (Fe²⁺) with ascorbic acid (Vitamin C).
- It does not dissociate in the gastrointestinal (GI) tract, ensuring efficient absorption and reducing the inhibitory effects of food on iron uptake.
- Mechanism of Action:
- Ascorbic Acid:
- Enhances the bioavailability of iron by maintaining it in the ferrous (Fe²⁺) state, which is more soluble and readily absorbed.
- Facilitates the transport of iron to storage sites in tissues.
- Acts as a reducing agent, preventing iron oxidation (to the less absorbable Fe³⁺ state) and aiding its incorporation into red blood cells.
- Iron:
- Essential for hemoglobin synthesis, which is critical for oxygen transport in the blood.
- Serves as a cofactor for enzymes like cytochromes, involved in energy production (electron transport chain).
- Helps in the formation of myoglobin and various enzymatic processes.
- Ascorbic Acid:
Folic Acid (Vitamin B9)
- Role in the Body:
- Necessary for nucleoprotein synthesis (DNA and RNA production).
- Supports normal erythropoiesis (red blood cell production), ensuring healthy oxygen transport.
- Prevents neural tube defects during early fetal development, making it vital for pregnant women.
- Metabolism:
- Folic acid is converted to its active form, tetrahydrofolic acid, in the liver and plasma via the enzyme dihydrofolate reductase.
- Involved in the synthesis of purines and thymidylate, critical for DNA replication.
Zinc
- Biological Importance:
- Acts as a cofactor for more than 100 enzymes, influencing various metabolic pathways.
- Crucial for DNA synthesis, cell division, and protein synthesis.
- Supports a healthy immune system, helping the body fight infections.
- Plays a role in maintaining the sense of smell and taste.
- May assist in the proper functioning of insulin, improving glucose metabolism.
This combination of ferrous ascorbate, folic acid, and zinc offers a comprehensive solution for:
- Treating iron-deficiency anemia.
- Supporting pregnancy and fetal development.
- Enhancing immune and enzymatic functions through adequate zinc levels.