-5%
Mirogabalin is a gamma-amino acid derivative with selective and potent affinity for α2δ subunits of voltage-gated calcium channels (VGCCs).
This reduces Ca²⁺ influx in dorsal root ganglion neurons and suppresses presynaptic neurotransmitter release.
The result is decreased neuronal hyperexcitability and pain signal modulation in neuropathic conditions.
Nervion (Mirogabalin) is indicated for the management of:
- Neuropathic pain
- Diabetic Peripheral Neuropathic Pain (DPNP)
- Postherpetic Neuralgia (PHN)
- Peripheral Neuropathic Pain (PNP)
