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Numira 5mg Tablet 1 Strip

SKU: 7177

Manufacturer: Beximco Pharmaceuticals Ltd.

Generic: Mirogabalin Besylate

Type: Tablet

Pack Size: 10pcs

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Description

Mirogabalin Besylate

  • Neuropathic Pain
  • Diabetic Peripheral Neuropathic Pain (DPNP)
  • Postherpetic Neuralgia (PHN)
  • Peripheral Neuropathic Pain (PNP)

Mirogabalin belongs to the class of gamma amino acids and their derivatives.

It selectively binds to the α2δ subunits of voltage-gated calcium channels (VGCCs). This reduces calcium influx and inhibits neurotransmitter release from presynaptic neurons, decreasing central nervous system (CNS) hyperexcitability.

  • Rapid absorption after oral intake, with a time to maximum plasma concentration of 0.5-1.5 hours.
  • Plasma protein binding is about 25%.
  • Excretion: 99% via kidneys, 1% via feces.

Half-life: 2-4.9 hours.