Numira 10 | 1 Strip | 15pcs
Numira 10 | 1 Strip | 15pcs Original price was: 525.00৳ .Current price is: 498.75৳ .
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Numira 5mg Tablet 1 Strip
Numira 5mg Tablet 1 Strip Original price was: 200.00৳ .Current price is: 190.00৳ .

Numira 2.5 | 1 Strip

SKU: 1309

Manufacturer: ACI Limited

Generic: Mirogabalin Besylate

Type: Tablet

Pack Size: 10 Pcs

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Original price was: 120.00৳ .Current price is: 114.00৳ .

Description

Numira Tablet is prescribed for the management of:

  • Neuropathic pain
  • Diabetic peripheral neuropathic pain (DPNP)
  • Postherpetic neuralgia (PHN)
  • Peripheral neuropathic pain (PNP)

Mirogabalin belongs to the gamma-aminobutyric acid derivative class. It selectively binds to α2δ subunits of voltage-gated calcium channels (VGCCs), reducing calcium influx and neurotransmitter release at presynaptic nerve endings. This mechanism decreases central nervous system (CNS) hyperexcitability, thereby alleviating neuropathic pain.

Absorption: Rapid after oral administration (Tmax: 0.5–1.5 hrs)

Protein binding: ~25% (low)

Distribution volume: 64–88 L

Elimination: Mainly excreted unchanged (61–72%) via the kidneys; 13–20% metabolized by UGT enzymes

Half-life: 2–4.9 hours

Excretion: ~99% through urine, ~1% via feces